We have carried out a long-term mircolensing survey program at Nainital using 1.04-m telescope during 1998-2002. To continue study of some of the interesting variables, we keep on following up our target field for next 10 years. In the process, we have detected microlensing event, Cepheid variables, Novae and eclipsing binaries. In this talk, I present photometric and spectroscopic analysis of the Hubble Sandage variable AF And in M31 for which we obtained R and I bands data for 169 nights spanning over about 5000 days. AF And has shown a prominent outburst around mid-January in 1999 followed up by a gradual decrease in brightness of about 1.5 mag in next 3 years with a declining rate of ~0.0015 mag/day. After lying low for about 9 years, this star has again gone through a secondary outburst phase in late 2010 with an amplitude of 0.5 mag where it lasted for one year before fading back to its quiescence phase. The emission line profiles in its spectrum yields a mass loss rate of about 6.6x10^-5 Msun/yr through the stellar winds in the photosphere. We estimate the photospheric temperature of 33,000+/-3000 K for this star during the visual minimum.