The burgeoning growth of human population and industrial development in developing countries, particularly South Asia, is accompanied by an increase of various air pollutants. However, their impact remains poorly quantified due to limited observations and a poor understanding of the emission sources, transport processes, and chemical evolution. The surface-based air pollution monitoring networks are important and essential, but they provide measurements at limited sites around any region and remain largely under-sampled. In contrast, space-based measurements offer a unique perspective on the state of our environment, from short to long term, and on local to global scale observations. The recent advent of downward-looking nadir hyperspectral instruments to probe the atmosphere from polar and geo orbiting satellites has substantially increased our ability to assess the impact of anthropogenic activities on the chemical composition of the atmosphere and their climatic implications. These measurements are performed using passive remote sensing in the UV, visible, and IR spectral regions. The inversion of geophysical parameters from the spectral signature of the atmosphere is obtained using a forward operator with a radiative transfer model and a minimization scheme. Additionally, we have utilized the FFNN ML technique. Here we will discuss (1) Assessments of geophysical parameters (T, WV, Ozone) from Indian geostationary satellite INSAT-3D/3DR with in-situ observations (2) Assessments of AIRS, IASI, and CrIS retrieved ozone products using balloon-borne observation and averaging kernel over the central Himalaya. (3) Long-term variations of environmentally important trace gases over the Himalayan foothills using measurements from the ground and space-based remote sensing and their intercomparisons (4) Radiance inter-calibration and improved retrieval algorithm for the Indian geostationary satellite to retrieve ozone and other meteorological parameters over a cloud-free scene (5) Utilization of satellite observations to study any air pollution episode: Remote sensing study of ozone, NO2, and CO: Some contrary effects of SARS-CoV-2 lockdown over India.